Mail Stop 6010 Via Facsimile and U.S. Mail September 16, 2005 Mr. James L. Fares President and Chief Executive Officer Questcor Pharmaceuticals, Inc. 3260 Whipple Road Union City, CA 94587 Re: Questcor Pharmaceuticals, Inc. Form 10-K for the fiscal year ended December 31, 2004 Filed March 31, 2005 File No. 1-14758 Dear Mr. Fares: We have completed our review of your Form 10-K and have no further comments at this time. Sincerely, Kevin Woody Branch Chief